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Crystal Structure of human NAMPT in complex with NVP-LVR596

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Crystal Structure of human NAMPT in complex with NVP-LVR596 Descriptor: (1S,2S)-N-{4-[(1S)-1-(propanoylamino)ethyl]phenyl}-2-(pyridin-3-yl)cyclopropane-1-carboxamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION Authors: Weihofen, W.A, Thigale, S. Deposit date: 2017-10-03 Release date: 2018-10-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Identification and structure based design of cellularly active cyclo-propyl carboxamide Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors To Be Published

人源烟酰胺磷酸核糖转移酶(Nicotinamide phosphoribosyltransferase, NAMPT)与NVP-LVR596的复合物晶体结构 组成描述:(1S,2S)-N-{4-[(1S)-1-(丙酰氨基)乙基]苯基}-2-(吡啶-3-基)环丙烷-1-甲酰胺、烟酰胺磷酸核糖转移酶(Nicotinamide phosphoribosyltransferase, NAMPT)、磷酸根离子 作者:Weihofen, W.A.、Thigale, S. 提交日期:2017-10-03 发布日期:2018-10-03 最后修改日期:2023-10-04 实验方法:X射线衍射(X-RAY DIFFRACTION,2.44 Å) 引用文献:《具有细胞活性的环丙基甲酰胺类烟酰胺磷酸核糖转移酶(NAMPT)抑制剂的发现与基于结构的设计》,待发表

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2017-10-03
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