Gene expression profile at single cell level of phagocytic myeloid cells in autochthonous lung cancer model
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE217368
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Phagocytosis is a critical process undertaken by myeloid cells in the tumor microenvironment. We used single-cell RNA-seq (scRNAseq) to investigate molecular and cellular consequences of neoplastic cell engulfment using a tdTomato genetically engineered mouse model. CD45-positive and CD45-negative populations from the lung tissue of SPC-creER KRAS-G12D mice were isolated by Fluorescence-activated cell sorting (FACS) analyzed using scRNAseq with antibody-based cell hashing.
创建时间:
2023-06-09



