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Genome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondria

ChEBI2014-11-03 更新2026-07-21 收录

RNA-DNA杂交体

RNaseH靶点鉴定

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-53420 数据链接链接失效反馈

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Genome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondria

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创建时间：

2014-11-03

RNA脱碱基位点

RNA-DNA杂交体

RNA abasic sites and the mechanisms involved in their regulation are mostly unknown; in contrast, DNA abasic sites are well-studied. We found surprisingly that in yeast and human cells, RNA abasic sit

NIAID Data Ecosystem80

Promoter-proximal R-loops regulate binding of chromatin regulators and pluripotency [RNA-seq]

RNA-DNA杂交体

染色质重塑

Numerous chromatin-remodelling factors are regulated by interactions with RNA. However, the contexts in which chromatin-remodelling factors encounter various RNA species, as well as the molecular func

干细胞与再生医学数据中心2022-02-20 更新60

NMR solution structure of a fully modified locked nucleic acid (LNA) hybridized to RNA

核酸结构解析

RNA-DNA杂交体

NMR solution structure of a fully modified locked nucleic acid (LNA) hybridized to RNA Descriptor: 5-D(*(LKC)P*(TLN)P*(LCG)P*(LCA)P*(TLN)P*(LCA)P* (TLN)P*(LCG)P*(LCC))-3, 5-R(*GP*CP*AP*UP*AP*UP*CP*AP*

Protein Data Bank Japan2026-06-24 更新20

Solution structure of LNA3:RNA hybrid

核酸结构生物学

RNA-DNA杂交体

Solution structure of LNA3:RNA hybrid Descriptor: 5- D(*CP*+TP*GP*AP*+TP*AP*+TP*GP*C) -3, 5- R(*GP*CP*AP*UP*AP*UP*CP*AP*G) -3 Authors: Petersen, M, Bondensgaard, K, Wengel, J, Jacobsen, J.P. Deposit d

Protein Data Bank Japan2024-05-15 更新70

Senataxin associates with replication forks to protect fork integrity across RNAPII transcribed genes. Saccharomyces cerevisiae

DNA复制叉

RNA-DNA杂交体

Here we analysed the role of yeast Senataxin (Sen1) in coordinating replication with transcription and in protecting genome integrity. Senataxin is mutated in the two severe neurodegenerative diseases

NIAID Data Ecosystem20

Genome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondria

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