Feeding with sustainably sourdough bread has the potential to promote the healthy microbiota metabolism at the colon level

Knowledge on environmental factors, which may compose the gut microbiota, and drive the host physiology and health, is of paramount importance. Human dietary habits and food compositions, pivotal drivers to assembly the human gut microbiota are challenging and, inevitably, unmapped for many diet components, which are poorly investigated individually. Approximately 30% of the human diet consists of fermented foods and beverages. Bread, a fermented/leavened food, is a basic component of the human diet. Its potential effect on gut microbiota composition and functionality is the new challenge. In this study, we industrially made baker`s yeast and sourdough breads, which were used to feed the Twin Mucosal-SHIME a worldwide scientifically validated gastrointestinal simulator. Only the consumption of sourdough bread has the potential to enhance the synthesis of short chain fatty acids and free amino acids at the colon level.