N6-adenosine methylation of mammalian miRNAs promotes their exosomal secretion. Homo sapiens
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m6A modificated miRNA in cells and tissues
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2024-02-28
相关数据集
LC-MS-MS-peak file-m6A/A%
m6A was quantitatively detected in mRNAs across mouse neurodevelopment in the cortex using LC-MS/MS. Both raw peak numbers and m6A/A% are provided.
NIAID Data Ecosystem130
m6A sites in the coding region trigger translation-dependent mRNA decay
m6A is the predominant internal RNA modification in messenger RNAs of eukaryotes (mRNAs), and plays a critical role in RNA stability. In this study, we reveal that m6A sites in the coding sequences (C
NIAID Data Ecosystem50
DYSREGULATION OF THE m6A EPITRANSCRIPTOME AS A NEW MECHANISM INVOLVED IN HIPPOCAMPAL-DEPENDENT MEMORY DEFECTS IN HD MICE. DYSREGULATION OF THE m6A EPITRANSCRIPTOME AS A NEW MECHANISM INVOLVED IN HIPPOCAMPAL-DEPENDENT MEMORY DEFECTS IN HD MICE
Recent advances in RNA biology have focused on a new layer of gene expression regulation termed Epitranscriptomics. One of the most common mRNA modifications that is highly abundant in brain is N6-met
NIAID Data Ecosystem30
METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer
Newly growing evidence highlights the essential role that epitranscriptomic marks play in the development of cancer; however, little is known about the role and implications of altered epitranscriptom
NIAID Data Ecosystem50
Lack of TRMT2A, a tRNA methyltransferase, induces the generation of tRNA-derived small RNAs due to m5U54 tRNA hypomodification [Seq]. Lack of TRMT2A, a tRNA methyltransferase, induces the generation of tRNA-derived small RNAs due to m5U54 tRNA hypomodification [Seq]
Transfer RNA (tRNA) molecules contain a variety of post-transcriptional modifications which are crucial for tRNA stability, translation efficiency, and fidelity. Besides their canonical roles in trans
NIAID Data Ecosystem40
