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Synthesis of Ferrocene-Based Pyridinones through Rh(III)-Catalyzed Direct C–H Functionalization Reaction

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https://figshare.com/articles/dataset/Synthesis_of_Ferrocene_Based_Pyridinones_through_Rh_III_Catalyzed_Direct_C_H_Functionalization_Reaction/3083539
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Synthesis of ferrocene-based pyridinones via Rh­(III)-catalyzed annulation of ferrocenecarboxamides with internal alkynes has been developed using a directing group as the internal oxidant. This method displays good functional group tolerance and delivers ferrocene-based pyridinones generally in moderate to good yields. Additionally, an asymmetric reaction can be achieved in the presence of a chiral catalyst Rh1.
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2016-05-17
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