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NABUCCO cohort 1 (NCT03387761) - Neo-Adjuvant Bladder Urothelial Carcinoma COmbination-immunotherapy

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ega-archive.org2025-03-26 收录
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https://ega-archive.org/datasets/EGAD00001006250
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NABUCCO cohort 1 sequencing data. The dataset includes:* Whole exome DNAseq pre-treatment on tumor samples (n=24) matched with blood samples (n=24)* RNAseq pre-treatment on tumor samples (n=18)* RNAseq post-treatment on tumor samples (n=18). Not all pre-treatment samples are linked with pre-treatment samples * High coverage Whole exome DNAseq on pre-treatment tumor samples (n=3) matched with post-treatment metastasized lymph nodes isolated with laser microdissection (n=3)* All samples are labelled with the response phenotype (Complete Responder or Non-Complete Responder)

NABUCCO队列1测序数据。该数据集包括:肿瘤样本的全面外显子组DNA测序预处理数据(n=24),与血液样本(n=24)相匹配;肿瘤样本的RNA测序预处理数据(n=18);肿瘤样本的RNA测序治疗后数据(n=18)。并非所有预处理样本都与预处理样本相连接;预处理肿瘤样本的高覆盖全面外显子组DNA测序数据(n=3),与治疗后转移性淋巴结(n=3)通过激光显微切割分离,且所有样本均标记了响应表型(完全响应者或非完全响应者)。
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