Data from: An uncommon cause of carotid artery dissection: Fabry disease.

Internal cervical artery dissection represent a common etiology of stroke
in the young, while the most common central nervous system manifestation
of Fabry Disease (FD) is acute cerebral ischemia. Nevertheless, internal
carotid artery disease has been scarcely associated with Fabry
Disease.  We describe the neuroimaging findings of an 49-year-old
patient presenting with acute left middle cerebral artery occlusion due to
an underlying internal carotid artery dissection. The patient was
successfully treated with intravenous thrombolysis and mechanical
thrombectomy. Further diagnostic work-up revealed bilateral cornea
verticillata and large-fiber polyneuropathy with impaired cold and warm
perception. Low a-galactosidase levels and molecular genetic testing
established the diagnosis of Fabry Disease, while the patient was started
on oral chaperone therapy with migalastat.  The present case
highlights that Fabry Disease may occasionally manifest with internal
carotid artery dissection and that FD should be included in the diagnostic
work-up of spontaneous internal carotid artery dissection.