Thesis Supplementary Tables
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Supplementary tables for thesis: Deciphering the genetic mechanisms underlying Alzheimer's Disease
Supplementary Table 2-1: Hi-C cell lines used to create tissue-specific GRNs
Supplementary Table 2-2: Two Sample Mendelian Randomisation (2SMR) identifies 179 genes across 9 tissues as causally associated with AD risk
Supplementary Table 2-3: 2SMR identifies KAT8 as the only gene present across 9 tissues as causally associated with AD risk
Supplementary Table 2-4: Location of SNPs tagging sceQTLs in relation to regulating gene which shows diverging tissue AD risk
Supplementary Table 3-1: Genes included in developmental enrichment analysis based on presence within the Allen Brain Atlas (ABA) RNA-seq datasets
Supplementary Table 3-2: Cutoff quantile thresholds of Allen Brain Atlas RNA-seq data for gene set enrichment analysis
Supplementary Table 3-3: Full Multimorbid3D pipeline results
Supplementary Table 3-4: Multimorbid3D pipeline results of the eight PPINs being investigated
Supplementary Table 3-5: KAT8:INO80E IBD/SLE PPIN gene set enrichment analysis results within the Allen Brain Atlas dataset
Supplementary Table 3-6: KAT8:INO80E IBD PPIN gene set enrichment analysis results within the gut dataset
Supplementary Table 3-7: KAT8:INO80E SLE PPIN gene set enrichment analysis results within the DICE immune cell dataset
Supplementary Table 3-8: BIN1 T2DM PPIN gene set enrichment analysis results within the Allen Brain Atlas dataset
Supplementary Table 3-9: KAT8 T2DM PPIN gene set enrichment analysis results within the Allen Brain Atlas dataset
Supplementary Table 3-10: PLEKHM1 T2DM PPIN gene set enrichment analysis results within the Allen Brain Atlas dataset
Supplementary Table 3-11: BIN1, KAT8 and PLEKHM1 T2DM PPIN gene set enrichment analysis results within the pancreas dataset
Supplementary Table 3-12: Depression gene set enrichment analysis results within the Allen Brain Atlas dataset
创建时间:
2025-07-01



