Genome-wide analysis of gene expression in brown adipose tissue (BAT) of mice lacking CD36

Analysis of gene expression in BAT lacking CD36. The hypothesis tested in the present study was that genes involved in lipid metabolism and mitochondrial function would be misregulated. Results provide important information about the role of CD36 in BAT. Total RNA was obtained from the BAT of control and Cd36-/- mice subjected to an overnight fast.缺失CD36的棕色脂肪组织（brown adipose tissue, BAT）的基因表达分析。本研究所验证的科学假说为：参与脂质代谢与线粒体功能的基因将出现表达失调。研究结果为阐明CD36在棕色脂肪组织中的作用提供了重要依据。本研究从经过夜禁食处理的野生型对照及Cd36基因敲除（Cd36-/-）小鼠的棕色脂肪组织中提取了总RNA。