Gender_Functional_Connectivity_Dataset

fMRI dataset from 48 healthy men and women (20 F) undergoing emotion regulation task (view/suppress emotional reaction to emotional pictures) and self-reported negative affect behavioral data. We were interested in whether men and women differed in their functional connectivity (FC) pattern while viewing versus regulating negative emotion induced by highly salient pictures, and whether this pattern related to their self-reported negative affect and suppression success. Despite women reporting more negative affect, both genders had comparable suppression success. Moreover, differences emerged between men and women’s FC patterns. During the regulation of negative emotion, better suppression in women was associated with stronger FC within a cingulo-opercular network, while men exhibited stronger FC within posterior regions of the ventral attentional network. We conclude that due to their propensity for higher emotional reactivity, women may employ a frontal top-down control network to downregulate negative emotion, while men may redirect attention away from the aversive stimulus by using posterior regions of the ventral attention network.本数据集纳入48名健康成年男女（其中女性20名），所有受试者均完成情绪调节任务——对情绪性图片执行观看或抑制情绪反应的操作，并采集了自我报告的消极情绪行为数据。本研究关注的核心问题为：在观看高显著性图片诱发的消极情绪，以及对该情绪进行调节的过程中，男女受试者的功能连接（functional connectivity, FC）模式是否存在差异，且该模式是否与自我报告的消极情绪程度及情绪抑制效果相关。尽管女性自我报告的消极情绪水平更高，但两类性别受试者的情绪抑制效果并无显著差异。此外，男女的功能连接模式确实存在显著差异：在消极情绪调节阶段，女性的情绪抑制效果越好，其扣带回-岛盖网络（cingulo-opercular network）内部的功能连接强度越高；而男性则表现为腹侧注意网络（ventral attentional network）后部区域的功能连接更强。综上，鉴于女性天生具有更高的情绪反应倾向性，其可能通过额叶自上而下的控制网络来下调消极情绪；而男性则可能借助腹侧注意网络的后部区域，将注意力从厌恶刺激上转移开来。