Topologically associating domains (TADs) are insufficient for the transcription of β-globin gene and sub-TADs are required for this process
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We found that TAD and sub-TAD contribute to enhancer-promoter interaction for gene transcription. H3K27me3 and H3K27ac ChIP-seq was performed in control and CTCF motifs-deleted (C3,7; dTAD or C4,5; dSub-TAD) MEL/ch11 cells to disrupt TAD or sub-TAD around the human β-globin locus.
创建时间：
2025-01-09
