High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to PN5-114.

High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to PN5-114. Descriptor: Tyrosine-protein kinase JAK2, {1-(ethylsulfonyl)-3-[4-(2-{[3-fluoro-4-(1-methylpiperidin-4-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile Authors: Karim, M.R, Schonbrunn, E. Deposit date: 2021-02-03 Release date: 2022-01-12 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.31 Å) Cite: High-resolution crystal structure of human Janus Kinase 2 kinase domain (JH1) bound to PN5-114. To Be Published

人类JAK2激酶结构域（JH1）与PN5-114结合的高分辨率晶体结构。
描述项：酪氨酸蛋白激酶JAK2（Tyrosine-protein kinase JAK2），{1-(乙磺酰基)-3-[4-(2-{[3-氟-4-(1-甲基哌啶-4-基)苯基]氨基}-7H-吡咯并[2,3-d]嘧啶-4-基)-1H-吡唑-1-基]氮杂环丁烷-3-基}乙腈
作者：Karim, M.R.、Schonbrunn, E.
提交日期：2021-02-03
发布日期：2022-01-12
最后修改日期：2024-11-06
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.31埃（Å）
引用信息：人类Janus激酶2（JAK2）激酶结构域（JH1）与PN5-114结合的高分辨率晶体结构，待发表。