Effect of aging on the meiotic cell cycle. Saccharomyces cerevisiae

Identify which stages of meiosis are impaired in replicative aging cells Transcriptional profile of aging yeast cells (young and old) incubated in sporulation-inducing conditions compared to new-born cells grown in vegetative conditions. Overall design: Two conditions experiments. Young and Old cells incubated in sporulation-inducing conditions. Control strain was same strain used for the experimental samples but grown in vegetative conditions.