RNA-seq in WTC11 i3 lower-motor neurons with and without TDP-43 knockdown
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RNA-seq in WTC11 i3 lower-motor neurons with and without TDP-43 knockdown
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2026-07-04
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Additional file 4: Tables S1 and S2. of Quantitative analysis of cryptic splicing associated with TDP-43 depletion
Quantification of all results for each cryptic exon discovered by CryptEx in mouse (ST1) and human (ST2). Change in percent spliced in (∆PSI) scores were calculated by taking the difference of ratios
NIAID Data Ecosystem70
Additional file 1 of Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function
Additional file 1: Supplementary Table 1. List of primers for cloning of shRNAs into pSIH. siRNA sequences are underlined. Supplementary Table 2. List of qPCR primers. Supplementary Table 3. List of t
NIAID Data Ecosystem60
Transcriptome analysis on TDP-43 downstream genes in Tardbp KO mice by Next Generation Sequencing
TDP-43 has been reported to be RNA-binding proteins; however their roles in mammary gland development has not been examined previously. Here, we performed RNA-seq on mammary gland of WT and Tardbp KO
NIAID Data Ecosystem40
Expression profiles of primary cortical neurons after knocking down Tdp-43. Mus musculus
To clarify the functional properties of Tdp-43, we established the differentially expressed alternative exons in Tdp-43-silenced primary cortical neurons by using exon-sensitive microarray technology.
NIAID Data Ecosystem60
The regulative role of DAXX in the gene expression in C9HRE ALS/FTD patient motor neurons. The regulative role of DAXX in the gene expression in C9HRE ALS/FTD patient motor neurons
To investigate the role of DAXX in the C9HRE-associated gene dysregulation inALS/FTD patient-derived motor neurons. Overall design: Two pairs of C9HRE ALS/FTD patient iPSCs and their isogenic controls
NIAID Data Ecosystem40
