Study of microRNA associated with metformin treatment in a mouse model of NASH(MCD)

ChEBI2015-03-01 更新2026-07-21 收录

非酒精性脂肪性肝病机制

microRNA药物反应研究

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-55523 数据链接链接失效反馈

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Study of microRNA associated with metformin treatment in a mouse model of NASH(MCD)

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2015-03-01

Hepatic transcriptome analysis of PRDX1fl/fl and Alb-Cre；PRDX1fl/fl mice on MCD. Hepatic transcriptome analysis of PRDX1fl/fl and Alb-Cre；PRDX1fl/fl mice on MCD

非酒精性脂肪性肝病机制

Jak-STAT信号通路

The etiology of non-alcoholic steatohepatitis (NASH) has been complicated. An increasing body of literature has indicated that hepatic oxidative stress exerts a causal role in driving NASH. Neverthele

NIAID Data Ecosystem100

Hepatic microRNA signatures in experimental nonalcoholic steatohepatitis. Hepatic microRNA signatures in experimental nonalcoholic steatohepatitis

非酒精性脂肪性肝病机制

肝脏microRNA生物标志物发现

Two-month-old C57BL/6J male mice were placed on chow diet or a diet enriched in high fat, cholesterol, and fructose (Research diet D09100301: 40 kcal% fat, 2% cholesterol, 20 kcal% fructose, HFCF diet

NIAID Data Ecosystem60

INSIG1 in NASH pathophysiology and in the hepatic wound-healing response. INSIG1 in NASH pathophysiology and in the hepatic wound-healing response

非酒精性脂肪性肝病机制

损伤修复分子机制

We investigated the biological function of INSIG1 in acute (CCl4) and chronic (NASH) liver damage. Male whole-body Insig1 wild-type (WT), Heterozygous (HET) and Knock-out (KO) mice were: 1) challenged

NIAID Data Ecosystem50

The targets and mechanisms of action of the AhR in NAFLD and other related diseases.

非酒精性脂肪性肝病机制

药物靶点发现

The targets and mechanisms of action of the AhR in NAFLD and other related diseases.

科学数据银行2025-05-07 更新70

Single Cell RNAseq analysis of mouse NASH liver cells

单细胞转录组学

非酒精性脂肪性肝病机制

The liver is undergoing major rearrangements during the development of non-alcoholic steatohepatitis (NASH), from steatosis to severe lipid accumulation, inflammation and fibrosis. The mechanisms for

NIAID Data Ecosystem50

Study of microRNA associated with metformin treatment in a mouse model of NASH(MCD)

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