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Supplementary files for study on modeling DSB with random forests
Structural variants (SVs) are known to play important roles in a variety of cancers, but their origins and functional consequences are still poorly understood. The nonrandom distributions of these var
DataCite Commons2023-04-27 更新100
Release of paused RNA-Polymerase II at specific introns and chromatin domains favors spontaneous DNA double strand break formation and predicts cancer translocations [ChIP-seq & BLISS]
Transcriptional activation leads to transient accumulation of DNA Double Strand Breaks (DSBs), which might promote formation of chromosomal translocations. We report here the genomic distribution of D
NIAID Data Ecosystem50
Cell type interchromosomal clustering.
Interactive 3D plot of interchromosomal DSB clustering for a range of cluster radii and LET for the three cell types: IMR90, GM12878 and HMEC. (HTML)
NIAID Data Ecosystem40
DNA double-strand breaks induced by AID in activated splenic B cells
Activation-induced cytidine deaminase (AID) is required for initiation of Ig class switch recombination (CSR) and somatic hypermutation (SHM) of antibody genes during immune responses. AID has also be
NIAID Data Ecosystem70
Molecular dynamics of DSB in nucleosome
These files contain the coordinate files (.gro) and compact trajectory files (.xtc) from the GROMACS runs of the nucleosome models O (experimental 1kx5), M1-M4 (model O with double strand breaks at va
DataCite Commons2020-08-30 更新50
