To investigate the tumor suppressor roleof CYB5R3 in lung cancer, we infected with adenoviral empty vector (EV) or CYB5R3 in NCI-H1299 cells. Overall design: We then performed gene expression profilin

NIAID Data Ecosystem30

Dissecting the contributions of cooperating cancer gene mutations to phenotype and drug susceptibility with patient-derived iPSCs

癌症基因功能研究

iPSC疾病模型

Isogenic iPSC models of SRSF2-mutant MDS

NIAID Data Ecosystem20

Lambda light chain knockdown in ALMC1 human myeloma cells

多发性骨髓瘤分子机制

siRNA基因敲低

We used siRNA to knockdown lambda light chain expression in ALMC1 cells that express an intact IgG lambda monoclonal protein. We compared knockdown cells to cells treated with control siRNA.

NIAID Data Ecosystem50

RNA-seq in HepG2 cells with YY1 knockdown. RNA-seq in HepG2 cells with YY1 knockdown

RNA测序分析

癌症基因功能研究

Dysregulation of YY1 has been observed in many human cancers. Recent studies have shown that overexpression of YY1 plays a pivotal role in the initiation and progression of nonalcoholic fatty liver di

NIAID Data Ecosystem30

siRNA knockdown of GALNT1 in hepatocellular carcinoma HA22T and PLC5 cells

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