S1 File - Force-Induced Dynamical Properties of Multiple Cytoskeletal Filaments Are Distinct from that of Single Filaments

Includes supporting figures and table. S1 Figure. (a) Phase diagram of microtubule in the force (f)-concentration (c) plane. The curve of mean wall-velocity demarcates between two phases, namely the bounded and unbounded growth phases. (b) and (c): Typical time traces of the wall position in the bounded phase. The trajectory of (b) shows that the system length (wall position) first shrinks rapidly with a negative velocity, but ultimately it fluctuates around a constant mean value — the later part is zoomed in (c), which shows catastrophes of the filament. (d) A typical trajectory of the system length in the unbounded growth phase, where grows in time with a positive velocity. Parameters are specified in Table 1 and inside the figure panels. S2 Figure. (a) Average cap size , (b) the diffusion constant for the system-length fluctuations, and (c) the diffusion constant for the fluctuations of switching events between capped and uncapped states — these are plotted against the scaled force . All data are for actin parameters (see Table 1) with a concentration and for . S1 Table. Comparison of values of stall forces obtained numerically by monitoring the limits , and . ATP/GTP Concentrations are taken to be for actin and for microtubule (for other parameters see Table 1). (PDF)