Deletion of the Lmna Gene in Fibroblasts Causes Senescence-Associated Dilated Cardiomyopathy

Deletion of Lmna in PDGFRA+ cells cause dilated cardiomyoapthy. Total RNA obtained from PDGFRA+ cells isolated from LV of WT and Pdgfra-Cre: LmnaF/Fmice were used for total RNA -seq.在PDGFRA阳性细胞（PDGFRA+ cells）中敲除Lmna可引发扩张型心肌病。本研究使用从野生型（Wild Type, WT）与Pdgfra-Cre:LmnaF/F小鼠的左心室（Left Ventricle, LV）中分离得到的PDGFRA阳性细胞所提取的总RNA，开展总RNA测序（total RNA-seq）实验。