Top 20 Predicted Regulatory Targets of Nkx2-1 Identified from a Consensus among Expression based Prediction, ChIP-seq, and Literature Evidence.

Regulatory targets are ranked in the increasing order of “Rank by CM”. The full set of candidate targets for consensus maximization consisted of genes that are differentially expressed in epithelial cells (p-valueNkx2-1 targets in lung epithelial cells. “Expression based Prediction (EP)” is based on the first-order conditional dependence inference described in the Methods. “ChIP-seq” is based on the result of previous Nkx2-1 ChIP-seq experiment: 1-represents the target has at least one predicted peak region; 0-means no predicted peak. “Literature Evidence 1” and “Literature Evidence 2” encodes the literature support from Ingenuity IPA (http://www.ingenuity.com/products/ipa) and Genomatix (https://www.genomatix.de), respectively. “Consensus Maximized Score (CM)” is the output of the consensus maximization. “Rank by EP” is the ranking of targets in the increasing order of the values in “Expression based Prediction (EP)”. “Rank by CM” is the ranking of targets in the decreasing order of the values in “Consensus Maximized Score (CM)”.Top 20 Predicted Regulatory Targets of Nkx2-1 Identified from a Consensus among Expression based Prediction, ChIP-seq, and Literature Evidence.