Deep insights into the gut microbial community of extreme longevity in south Chinese centenarians by ultra-deep metagenomics and large-scale culturomics
Abstract Sardinia, Italy, has a high prevalence of residents who live over 100 years. The reasons for longevity in this isolated region is currently unknown. Gut microbiota may hold a clue. To explore
Beta-glucan is a Dectin-1 agonist that is known to induce trained immunity, a process by which exposure to infectious agents or vaccination enhances the innate immune response to subsequent infection
The gut microbiome is emerging as a key regulator of several metabolic, immune and neuroendocrine pathways. Gut microbiome deregulation has been implicated in major conditions such as obesity, type 2
