Catalytic Functionalization of C–H Bonds of Azulene by Carbene/Nitrene Incorporation

The selective catalytic
functionalization of the C–H bond
of azulene upon incorporation of carbene or nitrene units with metal-based
catalysts is described. Ethyl diazoacetate or ArINTs are employed
as carbene or nitrene precursors, respectively. The azulene derivatives
are subsequently employed as building blocks toward more complex structures
with potential use as biodegradable materials.