Aromaticity-Dependent Regioselectivity in Pd(II)-Catalyzed C–H Direct Arylation of Aryl Ureas
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https://figshare.com/articles/dataset/Aromaticity_Dependent_Regioselectivity_in_Pd_II_Catalyzed_C_H_Direct_Arylation_of_Aryl_Ureas/2103190
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资源简介：
Palladium-catalyzed
C–H direct arylation generally occurs
on the ortho-position of directing groups. By comparing meta-arylated products of 2-naphthyl urea to ortho-arylated products of phenyl urea, the ortho- and meta-regioselectivity of aryl ureas were found to depend
on the aromaticity of the corresponding aryl substituents. Thus, aromaticity
is a new factor which can affect the regioselectivity in C–H
direct arylation. The finding was further confirmed by regioselective
direct arylation of indole and pyrrole derivatives.
创建时间：
2016-02-12
