Genes used for in vitro validation with corresponding targeting compounds and other uniquely essential genes.

We identified 7 uniquely essential genes to stomach associated pathogens (thyX, tktA, mqo, ndk, aroE, cdh, fumC) and reported their uniquely essential percentages. Two genes, fabF and fabZ are not uniquely essential genes, but are used as positive controls in the in vitro validation assay. Gene products, pathways that the gene is involved in are reported for all 9 genes, and the inhibitor, and inhibitor’s chemical formula are provided for the 3 genes that were used for in vitro validation and were not researched for genes not used for in vitro validation.