Locomotor capabilities of spinal rats in PBS- (SP-PBS) and BDNF-treated (SP-BDNF) groups evaluated during hindlimb walking on a moving treadmill.

Differences between scores achieved with- and without tail stimulation in SP-BDNF group in early post-operative period are significant (Wilcoxon test, P = 0.005). Differences between SP-PBS and SP-BDNF groups without tail stimulation in late post-operative period are also significant (Mann-Whitney U test; P = 0.02). NA – not analyzed.BBB scale modified by Antri and coworkers [54], [55] was used for assessment of bipedal treadmill locomotion in adult, spinalized rats. There are four major levels and 22 scores of recovery of motor capabilities, where level 4 and score 22 correspond to locomotion of intact animal. Animals were tested twice during the experiment, in the early and late post-operative period (exact testing days are shown).