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DAPPL Approach to the Identify Readers of Modified Cytosine

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA531722
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资源简介:
Epigenetic modifications of DNA in mammals play important roles in many biological processes. Identification of readers of these epigenetic marks is a critical step towards understanding the underlying molecular mechanisms. Here, we report the invention and application of an all-to-all approach, dubbed as DAPPL, to simultaneously profile human TF-DNA interactions using mixtures of random DNA libraries carrying four different epigenetic modifications.
创建时间:
2019-04-09
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