Discovery of Novel Small-molecule Inhibitors of PD-1/PD-L1 Axis that Promotes PD-L1 Internalization and Degradation
收藏Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Discovery of Novel Small-molecule Inhibitors of PD-1/PD-L1 Axis that Promotes PD-L1 Internalization and Degradation Descriptor: 2-[[3-[[5-(2-methyl-3-phenyl-phenyl)-1,3,4-oxadiazol-2-yl]amino]phenyl]methylamino]ethanol, Programmed cell death 1 ligand 1 Authors: Cheng, Y, Wang, T.Y, Lu, M.L, Jiang, S, Xiao, Y.B. Deposit date: 2021-01-20 Release date: 2022-01-26 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Discovery of Small-Molecule Inhibitors of the PD-1/PD-L1 Axis That Promote PD-L1 Internalization and Degradation. J.Med.Chem., 65, 2022
可促进程序性死亡受体配体1（PD-L1，Programmed cell death 1 ligand 1）内化与降解的程序性死亡受体1（PD-1，Programmed cell death 1）/PD-L1通路新型小分子抑制剂的发现
表征物：2-[[3-[[5-(2-甲基-3-联苯基)-1,3,4-噁二唑-2-基]氨基]苯基]甲氨基]乙醇，程序性死亡受体配体1（Programmed cell death 1 ligand 1）
作者：Cheng, Y、Wang, T.Y、Lu, M.L、Jiang, S、Xiao, Y.B.
收录日期：2021-01-20
发布日期：2022-01-26
最后更新日期：2024-10-16
检测方法：X射线衍射（X-RAY DIFFRACTION，2.42埃）
引用文献：Discovery of Small-Molecule Inhibitors of the PD-1/PD-L1 Axis That Promote PD-L1 Internalization and Degradation. 《药物化学杂志》（J.Med.Chem.），65卷，2022年
创建时间：
2021-01-20
