The external aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with cesium ion at the metal coordination site. The single beta-Q114 rotamer conformation allows a hydrogen bond to form with the PLP oxygen at the position 3 in the ring

The external aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with cesium ion at the metal coordination site. The single beta-Q114 rotamer conformation allows a hydrogen bond to form with the PLP oxygen at the position 3 in the ring Descriptor: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine, 1,2-ETHANEDIOL, 2-AMINOPHENOL, ... Authors: Hilario, E, Dunn, M.F, Mueller, L.J. Deposit date: 2020-08-11 Release date: 2021-08-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The external aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with cesium ion at the metal coordination site. The single beta-Q114 rotamer conformation allows a hydrogen bond to form with the PLP oxygen at the position 3 in the ring. To be Published

本数据集为鼠伤寒沙门氏菌（Salmonella typhimurium）色氨酸合酶（Tryptophan Synthase）突变体β-S377A与金属配位位点处铯离子结合形成复合物的外部醛亚胺晶体结构。该突变体的单一β-Q114旋转异构体构象可与环上3号位的吡哆醛磷酸（PLP）氧原子形成氢键。
描述符：(E)-N-({3-羟基-2-甲基-5-[(膦酰氧基)甲基]吡啶-4-基}亚甲基)-L-丝氨酸、1,2-乙二醇、2-氨基苯酚……
作者：Hilario, E、Dunn, M.F、Mueller, L.J.
提交日期：2020-08-11；发布日期：2021-08-25；最后修改日期：2023-10-18
实验方法：X射线衍射（分辨率1.7埃）
引用说明：鼠伤寒沙门氏菌色氨酸合酶突变体β-S377A与金属配位位点处铯离子结合形成复合物的外部醛亚胺晶体结构。该突变体的单一β-Q114旋转异构体构象可与环上3号位的PLP氧原子形成氢键。本成果待发表。