Cryo-EM structure of the potassium-selective channelrhodopsin HcKCR2 in lipid nanodisc

Cryo-EM structure of the potassium-selective channelrhodopsin HcKCR2 in lipid nanodisc Descriptor: (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, HcKCR2, PALMITIC ACID, ... Authors: Tajima, S, Kim, Y, Yamashita, K, Fukuda, M, Deisseroth, K, Kato, H.E. Deposit date: 2022-10-21 Release date: 2023-09-06 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (2.53 Å) Cite: Structural basis for ion selectivity in potassium-selective channelrhodopsins. Cell, 186, 2023

脂类纳米盘（lipid nanodisc）中钾选择性视紫红质通道HcKCR2的冷冻电镜（Cryo-EM）结构。描述符：(7R,17E,20E)-4-羟基-N,N,N-三甲基-9-氧代-7-[(棕榈酰氧基)甲基]-3,5,8-三氧杂-4-磷杂二十六碳-17,20-二烯-1-鎓4-氧化物、HcKCR2、棕榈酸（PALMITIC ACID）等。作者：Tajima S、Kim Y、Yamashita K、Fukuda M、Deisseroth K、Kato H.E.。存档日期：2022-10-21；发布日期：2023-09-06；最后修改日期：2024-10-16。实验方法：电子显微镜（分辨率2.53埃）。引用文献：《钾选择性视紫红质通道的离子选择性结构基础》，发表于《细胞（Cell）》2023年第186卷。