Supplementary information for files for "Effect of an acute session of intermittent exercise on trimethylamine N-oxide (TMAO) production following choline ingestion"

Supplementary files for article "Effect of an acute session of intermittent exercise on trimethylamine N-oxide (TMAO) production following choline ingestion"<b> Introduction</b>: Trimethylamine N-oxide (TMAO) is a gut bacteria-dependent metabolite associated with poor cardiovascular health. Exercise is a known cardioprotective activity but the impact of an acute bout of exercise on TMAO production is unknown.<b>Objectives/Methods</b>: This study assessed choline-derived production of TMAO following a single bout of intermittent exercise in a young, healthy cohort.<b>Results</b>: Choline supplemented after either exercise or a time-matched resting period demonstrated a similar increase in circulating TMAO across an 8-hour period.<b>Conclusion</b>: This suggests that a single bout of intermittent exercise does not alter gut microbial metabolic behaviour and thus does not provide additional cardioprotective benefits related to blood levels of TMAO.<br><br>©The Author(s) CC BY 4.0