China National GeneBank DataBase

The China National GeneBank database (CNGBdb) is a unified platform for biological big data sharing and application services. CNGBdb has now integrated a large amount of internal and external biological data from resources such as CNGB, NCBI, and the EBI. There are several sub-databases in CNGBdb, including literature, variation, gene, genome, protein, sequence, organism, project, sample, experiment, run, and assembly. Based on underlying big data and cloud computing technologies, it provides various data services, including archive, analysis, knowledge search, and management authorization of biological data. CNGBdb adopts data structures and standards of international omics, health, and medicine, such as The International Nucleotide Sequence Database Collaboration (INSDC), The Global Alliance for Genomics and Health GA4GH (GA4GH), Global Genome Biodiversity Network (GGBN), American College of Medical Genetics and Genomics (ACMG), and constructs standardized data and structures with wide compatibility. All public data and services provided by CNGBdb are freely available to all users worldwide. CNGB Sequence Archive (CNSA) is the bionomics data repository of CNGBdb. CNGB Sequence Archive (CNSA) is a convenient and efficient archiving system of multi-omics data in life science, which provides archiving services for raw sequencing reads and further analyzed results. CNSA follows the international data standards for omics data, and supports online and batch submission of multiple data types such as Project, Sample, Experiment/Run, Assembly, Variation, Metabolism, Single cell, and Sequence. Moreover, CNSA has achieved the correlation of sample entities, sample information, and analyzed data on some projects. Its data submission service can be used as a supplement to the literature publishing process to support early data sharing.CNGB Sequence Archive (CNSA) is a convenient and efficient archiving system of multi-omics data in the life science of CNGBdb, which provides archiving services for raw sequencing reads and further analyzed results. CNSA follows the international data standards for omics data, and supports online and batch submission of multiple data types such as Project, Sample, Experiment/Run, Assembly, Variation, Metabolism, Single cell, Sequence. Its data submission service can be used as a supplement to the literature publishing process to support early data sharing.

中国国家基因库数据库（CNGBdb）系生物大数据共享与应用服务的统一平台。CNGBdb现已整合来自CNGB、NCBI以及EBI等资源的大量内部及外部生物数据。该平台内设有多个子数据库，包括文献、变异、基因、基因组、蛋白质、序列、生物体、项目、样本、实验、运行和组装等。基于底层大数据和云计算技术，CNGBdb提供包括数据存档、分析、知识检索以及生物数据管理授权在内的多种数据服务。CNGBdb遵循国际基因组学、健康与医学领域的数据结构和标准，如国际核酸序列数据库合作组织（INSDC）、全球基因组与健康联盟（GA4GH）、全球基因组生物多样性网络（GGBN）、美国医学遗传学和基因组学学院（ACMG）等，构建了具有广泛兼容性的标准化数据和结构。CNGBdb提供的所有公共数据与服务均向全球用户免费开放。CNGB序列档案（CNSA）是CNGBdb的生物信息数据存储库。CNGB序列档案（CNSA）是生命科学领域多组学数据便捷高效的存档系统，为原始测序读数和进一步分析结果提供存档服务。CNSA遵循国际组学数据标准，支持项目、样本、实验/运行、组装、变异、代谢、单细胞和序列等多种数据类型的在线和批量提交。此外，CNSA在某些项目中实现了样本实体、样本信息和分析数据的关联。其数据提交服务可作为文献出版过程的补充，支持早期数据共享。

搜集汇总

背景与挑战

背景概述

China National GeneBank DataBase（CNGBdb）是一个综合性的生物大数据平台，整合了国内外多种生物数据资源，提供数据存档、分析和共享服务。该平台遵循国际标准，支持多种数据类型，并且所有公共数据对全球用户免费开放。