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Identification of neuron lineage-specific PRC1 targets in olfactory neuron precursors

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE124440
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The polycomb group protein, CBX8, is a neuron-specific component of Polycomb repressive complex 1 (PRC1) in the adult olfactory epithelium. We performed ChIP-seq to identify genes occupied by CBX8-PRC1. Examination of 2 PRC1 components, CBX8 and RING1B, and 2 histone marks, H3K27me3 and H3K27ac, in purified olfactory sensory neuron precursors; two biologic replicates per ChIP; input sequenced for every biologic replicate
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2020-12-27
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