Genome-wide genetic correlation estimates.

Genetic correlation estimates between each lipid trait and risk of all BCs, calculated by 2 methods. Lipid Trait: lipid trait used, Method: method used to estimate genetic correlation; Lipid intercept: estimate of lipid intercept from LDSC; Lipid intercept se: standard error of lipid intercept estimate from LDSC; Cross-trait intercept with BC-all: estimate of cross-trait intercept with risk of all BCs from LDSC; Cross-trait intercept se with BC-all: standard error of estimate of cross-trait intercept with risk of all BCs from LDSC; Genetic covariance: estimate of genetic covariance between lipid trait and BC; Covariance SE: standard error of genetic covariance estimate; Genetic correlation: estimate of genetic correlation between lipid trait and BC; Correlation SE: standard error of estimate of genetic correlation; Correlation Z-score: standard normalized estimate of genetic correlation; Correlation p-value: P-value of genetic correlation. BC, breast cancer; HDL, high-density lipoprotein; Hess, ρ-Hess method; LDL, low-density lipoprotein; LDSC, linkage disequilibrium-score regression; TC, total cholesterol; TG, triglycerides. (XLSX)