BALF bacterial-community profiles associated with erythromycin, AKT inhibition, and donor-source fecal microbiota transplantation in a Pseudomonas aeruginosa-induced bronchiectasis-like rat model: processed data and analysis resources

Processed 16S rRNA gene sequencing data and analysis resources supporting a rat Pseudomonas aeruginosa-induced bronchiectasis-like model study comparing erythromycin, CCT128930, and two fecal microbiota transplantation donor conditions. The dataset contains 96 specimens, including 48 bronchoalveolar lavage fluid samples and 48 fecal samples. Deposited materials include processed non-chimeric sequences, sample metadata, OTU abundance and taxonomic annotation tables, rarefied OTU data, genus-level relative-abundance data, manuscript-supporting statistical outputs, and reproducibility code for the core microbiome analyses. The original paired-end FASTQ files are no longer available; the deposited sequence FASTA represents post-QC, merged, chimera-filtered sequences. Because extraction/PCR negative-control sequence data were not recovered, low-biomass BALF taxonomic profiles should be interpreted with the contamination limitation described in the related manuscript.