Tuberculosis (TB) causes an estimated 2 million people per year globally. However, despite technological advances of the 21st century, there are no efficacious vaccines that prevent TB transmission. T
Footnotes: TB: tuberculosis; HIV: human immunodeficiency virus; n/N = number of positive tests/number of tested sera in each group; TST: tuberculin skin test (cut-off 5 mm); Cut-off value for PGL-Tb1:
Analysis of gene expression profiles identified a mycobacterial tRNA-induced innate immune network resulting in the robust production of IL-12p70, a cytokine required to instruct an adaptive Th1 respo
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is one of the leading infectious disease causes of morbidity and mortality worldwide. Though current antibiotic regimens can cure the disea
