Active Melanocortin-4 receptor (MC4R)- Gs protein complex bound to agonist NDP-alpha-MSH at 2.86 A resolution.

NIAID Data Ecosystem2026-05-02 收录

GPCR结构生物学

MC4R信号转导

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Active Melanocortin-4 receptor (MC4R)- Gs protein complex bound to agonist NDP-alpha-MSH at 2.86 A resolution.

创建时间：

2024-11-13

Structure of the A2A-StaR2-bRIL562-Compound 4e complex at 1.9A obtained from bespoke co-crystallisation experiments.

GPCR结构生物学

A2A腺苷受体拮抗剂

Structure of the A2A-StaR2-bRIL562-Compound 4e complex at 1.9A obtained from bespoke co-crystallisation experiments. Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-(3-amino-5-phenyl-1,2

Protein Data Bank Japan2024-10-23 更新60

Structure of nanobody AT209 in complex with the olmesartan-bound angiotensin II type I receptor (AT1R)

GPCR结构生物学

纳米抗体-受体复合物

Structure of nanobody AT209 in complex with the olmesartan-bound angiotensin II type I receptor (AT1R) Descriptor: BAG2 Anti-BRIL Fab Heavy Chain, BAG2 Anti-BRIL Fab Light Chain, CHOLESTEROL, ... Auth

Protein Data Bank Japan2025-03-26 更新40

Structural basis of class C metabotropic glutamate receptor 5 signal transduc...

GPCR结构生物学

受体信号转导

Metabotropic glutamate receptors (mGluR) are Class C GPCRs. They are obligate dimers, dimerization being fundamental for their function. mGluRs are activated by the binding of...

B2FIND20

Structure of the A2A-StaR2-bRIL562-Vipadenant complex at 2.6A obtained from in meso soaking experiments.

GPCR结构生物学

药物靶点复合物

Structure of the A2A-StaR2-bRIL562-Vipadenant complex at 2.6A obtained from in meso soaking experiments. Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[(4-azanyl-3-methyl-phenyl)methyl

Protein Data Bank Japan2024-10-23 更新50

Crystal structure of the CXCR4 chemokine receptor in complex with a small molecule antagonist IT1t in P1 spacegroup

GPCR结构生物学

趋化因子受体药物设计

Crystal structure of the CXCR4 chemokine receptor in complex with a small molecule antagonist IT1t in P1 spacegroup Descriptor: (6,6-dimethyl-5,6-dihydroimidazo[2,1-b][1,3]thiazol-3-yl)methyl N,N'-dic

Protein Data Bank Japan2024-10-16 更新30

Active Melanocortin-4 receptor (MC4R)- Gs protein complex bound to agonist NDP-alpha-MSH at 2.86 A resolution.

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