RSTR—LTBI Differentially expressed transcripts by condition.

Differentially expressed transcripts (DETs) for the RSTR—LTBI comparison are listed for the media (S1A worksheet) and Mtb stimulated conditions (S1B worksheet) and ranked by false discovery rate (FDR). Direction indicates whether expression is increased within the RSTR group (up) or LTBI group (down). Genes with ≥1 DET (FDR <0.05) are also noted (Y/N) if they were previously identified [8] as differentially expressed genes (DEGs) by the interaction term Mtb*RSTR using the lmekin interaction model (FDR <0.2). No significant DETs (FDR < 0.05) were identified by incorporating a similar Mtb*RSTR interaction model in Sleuth (S1C) without the kinship term. (XLSX)