George E. Palade (2011) CIL:7598, Cavia porcellus, hepatocyte. CIL. Dataset

This is a view of apical domains of two adjacent hepatocytes showing the junctional complexes that attach cells to one another. The canaliculus is defined by the cell membranes of two adjacent liver cells. At the level of the tight junctions (also known as zonula occludens) the intercellular spaces are sealed, thereby preventing leakage of bile from the canaliculus. Two adherens junctions (also known as zonula adherens) and two desmosomes are seen distal (relative to the canaliculus) to each tight junction. Glycogen particles are apparent in the cytoplasm of the liver cells. First description of tight junctions and the junctional complexes between epithelial cells from many tissues. Identical labeled image available as CIL# 7599. Image published as Figure 13 in Farquhar and Palade, 1963.

本图展示了相邻肝细胞的顶端区域，揭示了连接细胞彼此的接合复合体。胆管由相邻肝细胞的细胞膜界定。在紧密连接（亦称闭锁带）层面，细胞间隙被封闭，从而防止胆汁从胆管泄漏。每个紧密连接远端（相对于胆管而言）可见两个粘着带（亦称粘着带）和两个桥粒。肝细胞质中清晰可见糖原颗粒。此为首次描述多种组织上皮细胞之间的紧密连接及接合复合体。相同标记图像作为CIL# 7599号图像提供。图像发表于Farquhar和Palade，1963年的第13图。