BindingDB Entry 50018345: Systemic review on B-Raf

Name: BindingDB Entry 50018345: Systemic review on B-Raf
Creator: BindingDB
Published: 2024-04-26T22:57:49+08:00

DataCite Commons2024-04-26 更新2025-04-16 收录

肿瘤药物靶点验证

抑制剂筛选

数据链接：

https://www.bindingdb.org/entry/50018345 数据链接链接失效反馈

官方服务：

资源简介：

Small molecule binding data for protein Serine/threonine-protein kinase B-raf, Uniprot P15056 and P28028

提供机构：

BindingDB

创建时间：

2024-04-26

DYRK1a inhibitor mediated rescue of Drosophila models of Alzheimer’s disease-Down Syndrome phenotypes

神经退行性疾病模型

肿瘤药物靶点验证

Alzheimer’s disease (AD) is the most common neurodegenerative disease which is becoming increasingly prevalent due to ageing populations resulting in huge social, economic, and health costs to the com

NIAID Data Ecosystem100

BindingDB Entry 50018236: Reversible Lysine Specific Demethylase 1 (LSD1) Inhibitors: A Promising Wrench to Impair LSD1.

药物发现

蛋白质结合

Small molecule binding data for protein Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, Lysine-specific histone demethylase 1A, and REST corepressor 1, Uniprot O60341, P21397

DataCite Commons2024-04-26 更新70

Activity comparison for TBK1 and IKKε.

抑制剂筛选

药物发现

Number of active compounds (N) detected in each screen for total number detected (unfiltered), number after drug like filtering (filtered.drug-like), hits from the LOPAC and Kinase libraries, and the

NIAID Data Ecosystem50

BindingDB Entry 50018569: Discovery and Optimization of Potent and Orally Available CTP Synthetase Inhibitors for Use in Treatment of Diseases Driven by Aberrant Immune Cell Proliferation.

肿瘤药物靶点验证

抑制剂筛选

Small molecule binding data for protein CTP synthase 1 and CTP synthase 2, Uniprot P17812, P70303, P70698, Q5U2N0, and Q9NRF8

DataCite Commons2024-04-26 更新90

BindingDB Entry 50018636: Overview of piperlongumine analogues and their therapeutic potential.

配体-蛋白质相互作用

药物靶点筛选

Small molecule binding data for protein Aldo-keto reductase family 1 member B1, Uniprot P15121

DataCite Commons2024-04-26 更新70