Body Composition at Baseline and Changes on Study.

Data are mean (SD). Limb fat is the sum of fat in the arms and legs. The mean differences and 95% confidence intervals between treatment groups of the changes from baseline at weeks 2 and 14 were determined by unpaired t-tests. Differences between groups in changes from baseline that are statistically significant (P<0.05) are highlighted in bold. Asterisks (*) are used to indicate within-group changes from baseline that are statistically significant by paired t-test (P<0.05). Abbreviations: DEXA, dual energy X-ray absorptiometry; MRI, magnetic resonance imaging; CSA, cross-sectional area; SAT, subcutaneous adipose tissue; EMCL, extramyocellular fat (fat infiltration).