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Total Syntheses of All Stereoisomers of Phenatic Acid B

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https://figshare.com/articles/dataset/Total_Syntheses_of_All_Stereoisomers_of_Phenatic_Acid_B/2811685
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The total syntheses of all stereoisomers of phenatic acid B and determination of their absolute configuration are described. The synthetic strategy is based on an efficient combination of the Sharpless asymmetric dihydroxylation, the Johnson−Claisen rearrangement, and hydroboration−oxidation. It involves 11−12 steps and overall yield of 5−8%.
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2009-11-20
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