首页/数据集/Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease

Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease

NIAID Data Ecosystem2026-03-13 收录

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ADAM17

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE184877 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2022-01-27

B细胞分化与代谢重编程

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PKCb-null (Prkcb-/-) mice are severely immunodeficient. Here we show that mice whose B cells lack PKCb fail to develop germinal centers and plasma cells, which in concert undermine affinity maturation

NIAID Data Ecosystem100

MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization

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细胞生物学

Megakaryoblastic leukemia 1 (MKL1) promotes the regulation of essential cell processes, including actin cytoskeletal dynamics by co-activating serum response factor. Recently, the first human case wit

干细胞与再生医学数据中心2022-02-20 更新80

DataSheet_6_Lessons Learned From the Clinical Presentation of Common Variable Immunodeficiency Disorders: A Systematic Review and Meta-Analysis.pdf

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临床研究

BackgroundDiagnostic delay in common variable immunodeficiency disorders (CVID) is considerable. There is no generally accepted symptom-recognition framework for its early detection.ObjectiveTo system

frontiersin.figshare.com2023-06-05 更新70

Erratum: Common Variable Immunodeficiency: Etiological and Treatment Issues

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医学

One of the great advances in clinical medicine was the recognition of the pleomorphism of the immune response and the multiple afferent and efferent limbs of antigen processing and responsiveness. A s

DataCite Commons2025-06-01 更新100

Combined immunodeficiency with autoimmunity caused by a homozygous missense mutation in inhibitor of nuclear factor kappa-B kinase alpha

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自身免疫

This study aims to identify the mechanisms underlying a primary immune disorder with autoimmune features

NIAID Data Ecosystem70