首页/数据集/Loss of multi-level 3D genome organization during breast cancer progression - Processed LAD files

Loss of multi-level 3D genome organization during breast cancer progression - Processed LAD files

NIAID Data Ecosystem2026-05-02 收录

乳腺癌三维基因组

核纤层相关结构域分析

数据链接：

https://zenodo.org/record/13255504 数据链接链接失效反馈

官方服务：

资源简介：

This entry contains the processed LAD files produced as part of the following study:Loss of multi-level 3D genome organization during breast cancer progression

应用场景：

创建时间：

2024-08-07

乳腺癌三维基因组

RUNX1

RUNX1 is a transcription factor functioning both as an oncogene and a tumor suppressor in breast cancer. RUNX1 alters chromatin structure in cooperation with chromatin modifier and remodeling enzymes.

NIAID Data Ecosystem80

A molecular mechanism for compartmentalization and silencing of chromatin domains at the nuclear lamina [Tiling Array]

核纤层相关结构域分析

染色体空间组织

These are the tiling array data for the experiments describing LADs on murine chromosomes 5, 12, and 15 by Dam-ID, as determined by LMNB and EMD Dam tagging and detection experiments Supplemental Bed

NIAID Data Ecosystem10

Deterioration of multi-level 3D genome organization during breast cancer progression

乳腺癌三维基因组

染色质构象

Breast cancer progression entails intricate, multi-level alterations in genome organization and expression. To gain insights into the modifications in chromatin's three-dimensional (3D) structure duri

NIAID Data Ecosystem00

Genome-wide maps of LADs distribution in control and Dam-WT/Dam-R527C LMNA stabilized Hela cells

核纤层相关结构域分析

LMNA点突变功能研究

To determine if LMNA R527C mutation affect the arrangement and function of LADs, we performed Lamin A DamID-seq in wild type and mutant LMNA-stablized Hela cells. Reads of Lamin A ChIP-seq in LADs wer

NIAID Data Ecosystem40

Deterioration of multi-level 3D genome organization during breast cancer progression

乳腺癌三维基因组

染色体构象捕获（Hi-C）

NIAID Data Ecosystem10