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Solution Structure of Antibiotic-Resistance Factor ANT(2'')-Ia Reveals Substrate-Regulated Conformation Dynamics

NIAID Data Ecosystem2026-05-02 收录

细菌耐药性机制

构象动力学

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Solution Structure of Antibiotic-Resistance Factor ANT(2'')-Ia Reveals Substrate-Regulated Conformation Dynamics

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2024-05-15

细菌耐药性机制

细菌代谢干预治疗

Exogenous pyruvate promotes gentamicin uptake to kill antibiotic-resistant Vibrio alginolyticus

integrated proteome resources30

Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens. Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens

细菌耐药性机制

tRNA微阵列分析

We present evidence of mechanistically diverse allosteric relays converging on a few peptidyltransferase center (PTC) nucleotides, and propose a general model of antibiotic resistance mediated by thes

NIAID Data Ecosystem10

aANM data for the transition of a GroEL subunit between R�� and T forms(*).

构象动力学

结构生物学

(*)mT(k) and mR��(k) are the number of modes recruited at step k, starting from the respective states R�� and T; RMSD values are calculated using Eq. (3). A and B designate the respective states T and

Figshare2015-12-02 更新00

ReGAIN Supplemental Figures

细菌耐药性机制

基因共现网络分析

The rampant rise of multidrug-resistant (MDR) bacterial pathogens poses a serious health threat, necessitating innovative tools to unravel the complex genetic underpinnings of antimicrobial resistance

Figshare2025-05-08 更新10

Table_2_Characterization and Identification of a novel chromosome-encoded metallo-β-lactamase WUS-1 in Myroides albus P34.DOCX

新型β-内酰胺酶鉴定

细菌耐药性机制

In this study, we identified and characterized a novel chromosomally-encoded class B metallo-β-lactamase (MBL) gene designated blaWUS-1 in a carbapenem-resistant isolate Myroides albus P34 isolated fr

NIAID Data Ecosystem10

Solution Structure of Antibiotic-Resistance Factor ANT(2'')-Ia Reveals Substrate-Regulated Conformation Dynamics

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