Gene interactions identified in the T-cell activation network.

Links whose direction cannot be changed without changing the probabilistic relations encoded are named arcs, otherwise they are edges. If there is an arc from gene A to another gene B, then we say that A is a parent of B and B is a child of A. The relative weight was measured with the Kullback-Leibler (KL) divergence indicating the contribution of each link with respect to the complete network structure (see methods). The category indicates whether the interactions were previously reported in the literature or identified in the co-expression Ingenuity database (predicted) or not (new). The orientation indicates if the direction of the causal influence for the predicted interactions was the same as that in the structural network (right) or the opposite (reverse).