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Total Synthesis of Natural <i>p</i>‑Quinol Cochinchinenone

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NIAID Data Ecosystem2026-03-07 收录
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Cochinchinenone has been synthesized in only five steps and four pots and in 58% overall yield from commercially available 2,3-dimethoxy-4-hydroxy-benzaldehyde and OPMB-protected p-hydroxy acetophenone, the key step being the oxone-mediated oxidative dearomatization of the corresponding ketone-containing p-substituted phenol.

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2012-12-07
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