Synthesis of Isothiazoles and Isoselenazoles through Rhodium-Catalyzed Oxidative Annulation with Elemental Sulfur and Selenium
收藏NIAID Data Ecosystem2026-03-12 收录
下载链接：
https://figshare.com/articles/dataset/Synthesis_of_Isothiazoles_and_Isoselenazoles_through_Rhodium-Catalyzed_Oxidative_Annulation_with_Elemental_Sulfur_and_Selenium/13369448
下载链接
链接失效反馈官方服务：
资源简介：
A rhodium-catalyzed oxidative annulation
of benzimidates with elemental
sulfur for the direct construction of isothiazole rings is reported.
The proposed reaction mechanism involving Rh(I)/Rh(III) redox is supported
by a stoichiometric reaction of metallacycle species as well as DFT
calculations. This method is also applicable to selenium cyclization
to produce isoselenazole derivatives. The alkoxy substituent at C3
can be used for further functionalization of the azole core.
创建时间：
2020-12-11
