CUSP9v3-U3118-part1

Label-free live-cell imaging and endpoint cell viability data obtained from exposing the patient derived glioblastoma cell line U3118 (see related article below), on all single drugs of the CUSP9v3 protocol up to all combinations of order 4. The standard-of-care drug, temozolomide, was also used as a single treatment as well as add-on to all combinations. There are 4 .zip files containing all the imaging data, one for each 384-well plate used. Every .zip file contains 5544 grayscale images of size 800x992 pixels and every experimental well consists of a temporal sequence of 18 such images. The experiment was performed in quadruplicate and the associated plate layouts used for acoustic liquid dispension are also included as .xlsx files. The .log file contains the cell viability data for all plates.本数据集涵盖通过对患者来源胶质母细胞瘤细胞系U3118（详见下文相关文章）施加CUSP9v3方案的全部单药乃至4阶所有联合用药处理所获得的无标记活细胞成像（Label-free live-cell imaging）与终点细胞活力数据。标准治疗药物替莫唑胺（temozolomide）既以单药形式开展处理，也作为附加药物应用于所有联合用药方案。 本数据集包含4个.zip压缩包，涵盖全部成像数据，每个压缩包对应一块所用的384孔板。每个压缩包内含5544张尺寸为800×992像素的灰度图像，每个实验孔对应由18张该类图像组成的时序序列。本实验采用四重复实验设计，用于声学液体分配的配套孔板布局文件也以.xlsx格式附带提供。.log文件则收录了所有孔板的细胞活力数据。