Structure of Interleukin-6 in complex with a Camelid Fab fragment
收藏Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Structure of Interleukin-6 in complex with a Camelid Fab fragment Descriptor: Heavy Chain of the Camelid Fab fragment 61H7, Interleukin-6, Light Chain of the Camelid Fab fragment 61H7 Authors: Klarenbeek, A, Blanchetot, C, Schragel, G, Sadi, A.S, Ongenae, N, Hemrika, W, Wijdenes, J, Spinelli, S, Desmyter, A, Cambillau, C, Hultberg, A, Kretz-rommel, A, Dreier, T, De haard, H.J.W, Roovers, R.C. Deposit date: 2014-01-02 Release date: 2015-04-15 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Combining residues of naturally-occurring Camelid somatic affinity variants yields ultra-potent human therapeutic IL-6 antibodies To be Published
白细胞介素-6（Interleukin-6）与骆驼科Fab片段的复合物结构
描述项：骆驼科Fab片段61H7重链、白细胞介素-6、骆驼科Fab片段61H7轻链
作者：Klarenbeek, A、Blanchetot, C、Schragel, G、Sadi, A.S、Ongenae, N、Hemrika, W、Wijdenes, J、Spinelli, S、Desmyter, A、Cambillau, C、Hultberg, A、Kretz-rommel, A、Dreier, T、De haard, H.J.W、Roovers, R.C.
保藏日期：2014-01-02
发布日期：2015-04-15
最后修改日期：2024-10-30
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.42埃（Å）
引用文献：结合天然存在的骆驼科体细胞亲和力变体的残基可获得超强效人治疗性IL-6抗体（待发表）
创建时间：
2014-01-02
